The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Apr. 15, 2011
Applicants:

Dangshe MA, Millwood, NY (US);

Kirsten Nagashima, Valhalla, NY (US);

Brian Kennedy, Yorktown Heights, NY (US);

Gerald P. Donovan, Kittery, ME (US);

Yun Kang, Livingstone, NJ (US);

William C. Olson, Yorktown Heights, NY (US);

Shankar Kumar, Pleasanton, CA (US);

Naoya Tsurushita, Palo Alto, CA (US);

Andre J. Marozsan, Port Chester, NY (US);

Albert Cupo, Stamford, CT (US);

Inventors:

Dangshe Ma, Millwood, NY (US);

Kirsten Nagashima, Valhalla, NY (US);

Brian Kennedy, Yorktown Heights, NY (US);

Gerald P. Donovan, Kittery, ME (US);

Yun Kang, Livingstone, NJ (US);

William C. Olson, Yorktown Heights, NY (US);

Shankar Kumar, Pleasanton, CA (US);

Naoya Tsurushita, Palo Alto, CA (US);

Andre J. Marozsan, Port Chester, NY (US);

Albert Cupo, Stamford, CT (US);

Assignee:

Progenics Pharmaceuticals, Inc., Tarrytown, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/40 (2006.01); C07K 16/12 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1282 (2013.01); A61K 39/40 (2013.01); A61K 45/06 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/55 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

Provided herein are reagents, compositions, and therapies with which to treatinfection and related disease conditions and pathologies, such as-associated diarrhea, resulting from infection bybacteria and the enterotoxins produced by these bacteria. In particular, antibodies or antigen-binding fragments thereof that bind specifically to toxin A and/or toxin B ofand neutralize the activities of these toxins; compositions comprising such antibodies; and methods of using the antibodies and the compositions are provided.


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