The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
Aug. 27, 2010
Pierre LI, Burlingame, CA (US);
Yaohuang KE, Burlingame, CA (US);
Yongke Zhang, Burlingame, CA (US);
Weimin Zhu, Burlingame, CA (US);
Guoliang Yu, Burlingame, CA (US);
Fanxin MA, Nanjing, CN;
Xin Fan, Nanjing, CN;
Pierre Li, Burlingame, CA (US);
Yaohuang Ke, Burlingame, CA (US);
Yongke Zhang, Burlingame, CA (US);
Weimin Zhu, Burlingame, CA (US);
Guoliang Yu, Burlingame, CA (US);
Fanxin Ma, Nanjing, CN;
Xin Fan, Nanjing, CN;
Jiangsu Simcere Pharmaceutical R & D Co., Ltd., Jiangsu, CN;
Apexigen Inc., Burlingame, CA (US);
Abstract
The present invention provides an anti-VEGF monoclonal antibody, which has the variable region of heavy chain comprising the amino acid sequences of SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3, and/or the variable region of light chain comprising the amino acid sequences of SEQ ID NO:4, SEQ ID NO:5 and SEQ ID NO:6. The antibody can be produced by the cell line with the preservation number of CGMCC NO. 3233. The invention also provides the use of said antibody for the manufacture of medicaments for the treatment of a disease that is relevant to VEGF, wherein further provided are pharmaceutical composition, agents, kits and chips comprising said antibody, as well as the cell line with the preservation number of CGMCC NO. 3233.