The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2015

Filed:

Nov. 15, 2010
Applicants:

Ana Martin-vilalba, Heidelberg, DE;

Peter Herhaus, Heidelberg, DE;

Ignacio Sancho-martinez, La Jolla, CA (US);

Susanne Kleber, Heidelberg, DE;

Thilo Welsch, Heidelberg, DE;

Inventors:

Ana Martin-Vilalba, Heidelberg, DE;

Peter Herhaus, Heidelberg, DE;

Ignacio Sancho-Martinez, La Jolla, CA (US);

Susanne Kleber, Heidelberg, DE;

Thilo Welsch, Heidelberg, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); G01N 33/50 (2006.01); A61K 31/7105 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5041 (2013.01); G01N 33/5011 (2013.01); A61K 31/7105 (2013.01); G01N 2333/70578 (2013.01);
Abstract

The present invention is concerned with compounds inhibiting CD95 signaling in pancreatic cancer cells. Furthermore, contemplated by the current invention are medicaments comprising such a compound for the prevention and/or treatment of pancreatic cancer as well as the use of such a compound for the manufacture of a medicament for the prevention and/or treatment of pancreatic cancer, the prevention of migration of cancer cells, and/or the prevention and/or treatment of an inflammatory reaction. The present invention also refers to a method for the identification of a compound inhibiting CD95 signaling, as we to a method for the manufacture of a medicament comprising the steps of the method for the identification of a compound inhibiting CD95 signaling and the further step of formulating the inhibiting compound as a medicament.


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