logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8986657 B1

PDFFull Text
Expired
Date of Patent:
Mar. 24, 2015

Filed:

Jul. 29, 2010

Methods and system for detecting soluble amyloid-β

Applicants:

Chongzhao Ran, Winchester, MA (US);

Anna Moore, Dracut, MA (US);

Inventors:

Chongzhao Ran, Winchester, MA (US);

Anna Moore, Dracut, MA (US);

Assignee:

The General Hospital Corporation, Boston, MA (US);

Attorney:

Quarles & Brady, LLP

Primary Examiner:

Michael G Hartley

Assistant Examiner:

Jennifer Lamberski

Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/055 (2006.01); C07F 5/02 (2006.01); C07D 213/02 (2006.01); G01N 33/566 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
C07F 5/022 (2013.01); C07D 213/02 (2013.01); G01N 33/566 (2013.01); G01N 33/585 (2013.01); G01N 2333/4709 (2013.01);
Abstract

The present invention provides methods of detecting soluble amyloid β using curcumin-derived near infrared (NIR) imaging probes. Upon interacting with soluble amyloid β, these probes undergo a range of changes, qualifying them as 'smart' probes. In addition, the invention provides methods of detecting soluble amyloid β by positron emission tomography (PET), magnetic resonance imaging (MRI) and multimodal imaging based on the curcumin-derived NIR imaging probes and derivatives thereof.

Find Patent Forward Citations

Ran, Chongzhao. (2015). Methods and system for detecting soluble amyloid-β (U.S. Patent No. 8986657). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8986657

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…