The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2015

Filed:

Aug. 26, 2011
Applicants:

James C. Samuelson, Newburyport, MA (US);

Carine Robichon-iyer, Cambridge, MA (US);

Jianying Luo, Ipswich, MA (US);

Inventors:

James C. Samuelson, Newburyport, MA (US);

Carine Robichon-Iyer, Cambridge, MA (US);

Jianying Luo, Ipswich, MA (US);

Assignee:

New England Biolabs, Inc., Ipswich, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 1/22 (2006.01); C07K 1/36 (2006.01); A61K 39/00 (2006.01); C12N 9/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/93 (2013.01); C12N 2810/55 (2013.01); C12Y 601/01007 (2013.01);
Abstract

Compositions relating to a combination of two types of separation matrix; and to variant host cells which contain at least one essential host protein that is fused to an affinity binding tag or has been mutated to replace at least two of a plurality of histidines or basic amino acids are provided. Methods are also provided that relate to isolating a recombinant protein from a lysate.


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