The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2015
Filed:
May. 05, 2011
Applicants:
Rainer Schobert, Zell, DE;
Bernhard Biersack, Prebitz, DE;
Thomas Müller, Halle, DE;
Inventors:
Assignees:
Universitat Bayreuth, Bayreuth, DE;
Martin-Luther-Universitat Halle-Wittenberg, Halle, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4164 (2006.01); A61K 31/4178 (2006.01); A61K 31/42 (2006.01); C07D 233/64 (2006.01); C07D 263/32 (2006.01); C07D 403/04 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01); C07D 233/58 (2006.01); C07D 403/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4164 (2013.01); A61K 31/4178 (2013.01); A61K 31/42 (2013.01); A61K 45/06 (2013.01); C07D 233/64 (2013.01); C07D 263/32 (2013.01); C07D 403/04 (2013.01); A61N 5/10 (2013.01); C07D 233/58 (2013.01); C07D 403/10 (2013.01);
Abstract
The present invention relates to specific analogs of combretastatin, in particular the compounds of formula (I) as described and defined herein, and pharmaceutical compositions comprising the compounds, as well as their medical use, in particular in the treatment or prevention of cancer, including multidrug-resistant cancer.