The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2015
Filed:
Dec. 21, 2011
Philippe Lambin, Genappe Bousvalle, BE;
Jean-yves Winum, Saint Andre de Sangonis, FR;
Claudiu Supuran, Florence, IT;
Philippe Lambin, Genappe Bousvalle, BE;
Jean-Yves Winum, Saint Andre de Sangonis, FR;
Claudiu Supuran, Florence, IT;
Stichting Maastricht Radiation Oncology “Maastro-Clinic”, Maastricht, NL;
Université Montpellier 2 Sciences et Techniques, Montpellier, FR;
Other;
Abstract
The present invention concerns novel carbonic anhydrase IX inhibitors comprising a nitroimidazole moiety and their use in therapy of hypoxic conditions, in particular cancer treatment, especially chemotherapy and radiotherapy. The compounds of the invention have an increased specificity for the carbonic anhydrase IX enzyme compared to the art. The present invention relates to novel nitroimidazole derivates represented by formula (1).