The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2015
Filed:
May. 27, 2014
Applicant:
Virginia Commonwealth University, Richmond, VA (US);
Inventors:
Yan Zhang, Glen Allen, VA (US);
Dana E. Selley, Richmond, VA (US);
William Dewey, Richmond, VA (US);
Assignee:
Virginia Commonwealth University, Richmond, VA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/485 (2006.01); C07D 489/08 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C07D 489/08 (2013.01); G01N 33/53 (2013.01); G01N 2500/04 (2013.01);
Abstract
Selective, non-peptide antagonists of the mu opioid receptor (MOR) and methods of their use are provided. The antagonists may be used, for example, to identify MOR agonists in competitive binding assays, and to treat conditions related to addiction in which MOR is involved, e.g. heroin, prescription drug and alcohol addiction, as well as in the treatment of opioid induced constipation (OIC).