The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2015

Filed:

Aug. 07, 2014
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Richard V. Connors, Pacifica, CA (US);

Kang Dai, Albany, CA (US);

John Eksterowicz, San Francisco, CA (US);

Pingchen Fan, Fremont, CA (US);

Benjamin Fisher, San Mateo, CA (US);

Jiasheng Fu, Foster City, CA (US);

Kexue Li, Mountain View, CA (US);

Zhihong Li, Millbrae, CA (US);

Lawrence R. McGee, Pacifica, CA (US);

Rajiv Sharma, Fremont, CA (US);

Xiaodong Wang, Millbrae, CA (US);

Dustin L. McMinn, Pacifica, CA (US);

Jeffrey T. Mihalic, San Francisco, CA (US);

Jeffrey Deignan, San Francisco, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 491/147 (2006.01); C07D 471/14 (2006.01); C07D 471/04 (2006.01); C07D 487/14 (2006.01); C07D 491/107 (2006.01); C07D 498/10 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); C07D 471/04 (2013.01); C07D 487/14 (2013.01); C07D 491/107 (2013.01); C07D 498/10 (2013.01); C07D 498/04 (2013.01); C07D 491/147 (2013.01);
Abstract

Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of CDK4-mediated disorders, such as cancer. The subject compounds are fused pyridine, pyrimide and triazine derivatives.


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