The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2015
Filed:
Apr. 13, 2012
Mario Varasi, Milan, IT;
Florian Thaler, Gerenzano, IT;
Raffaella Amici, Codogno, IT;
Agnese Abate, Philadelphia, PA (US);
Maria Carmela Fulco, Milan, IT;
Saverio Minucci, Noverasco di Opera, IT;
Ciro Mercurio, Legnano, IT;
Mario Varasi, Milan, IT;
Florian Thaler, Gerenzano, IT;
Raffaella Amici, Codogno, IT;
Agnese Abate, Philadelphia, PA (US);
Maria Carmela Fulco, Milan, IT;
Saverio Minucci, Noverasco di Opera, IT;
Ciro Mercurio, Legnano, IT;
DAC S.R.L., Milan, IT;
Abstract
This invention is related to new histone deacetylase inhibitors according to the general formula (I), wherein: m and n are independently zero or an integer from 1 to 4; p is zero or an integer from 1 to 3, with the proviso that when p is zero, n and m cannot be both 1; R is hydrogen; C-Calkyl, optionally substituted by C-Ccycloalkyl, C-Caryl or hetero(C-C)aryl; (CO)R; (SO)R; C-Ccycloalkyl; C-Caryl; or hetero(C-C)aryl; Ris halogen, C-Calkyl, C-Chaloalkyl, C-Calkoxy, C-Chaloalkoxy; Y is CHor NR; Z is C═R; and R, R, R, and Rare as further defined in the specification; and pharmaceutical acceptable salts thereof.