The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2015

Filed:

Jan. 30, 2009
Applicants:

Chaouki Miled, Antony, FR;

Frédéric Tangy, Les Lilas, FR;

Yves Jacob, Maintenon, FR;

Inventors:

Chaouki Miled, Antony, FR;

Frédéric Tangy, Les Lilas, FR;

Yves Jacob, Maintenon, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C07K 14/08 (2006.01); A61P 37/02 (2006.01); C12N 15/63 (2006.01); C12Q 1/02 (2006.01); C12N 1/19 (2006.01); C12P 21/00 (2006.01); C12N 7/00 (2006.01); A61K 39/165 (2006.01); C12N 15/81 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 39/165 (2013.01); C12N 15/81 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5258 (2013.01); C12N 2760/00051 (2013.01); C12N 2760/18434 (2013.01); C12N 2760/18451 (2013.01);
Abstract

The present invention relates to a methodology for the generation of infectious ribonucleoparticles (RNPs) of negative-strand RNA viruses, and in particular of non-segmented negative-strand RNA viruses in yeast, especially in budding yeast. Accordingly, the patent application relates to a recombinant yeast strain suitable for the rescue of infectious non-segmented negative-strand RNA virus particles or infectious virus-like particles. The invention also relates to the use of the recombinant yeast to prepare vaccine seed and to the use of the produced RNPs or RNPs-like to prepare vaccine formulations. It also concerns the use of the recombinant yeast for the screening of libraries of DNA.


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