The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2015
Filed:
Nov. 21, 2007
Applicant:
Takashi Kondo, Saitama, JP;
Inventor:
Takashi Kondo, Saitama, JP;
Assignee:
Riken, Saitama, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12P 21/06 (2006.01); C07H 21/04 (2006.01); A01K 67/027 (2006.01); C07K 14/47 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0275 (2013.01); C07K 14/4705 (2013.01); C12N 15/8509 (2013.01); A01K 2217/052 (2013.01); A01K 2217/072 (2013.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); A01K 2267/0393 (2013.01); C12N 2830/40 (2013.01);
Abstract
This invention relates to a method for stably expressing a transgene integrated into the genome of an animal cell or of an animal over a long period. Specifically, this invention provides: an approximately 2.5 kb XhoI-BamHI fragment (or XB fragment) derived from the Evx2-Hoxd13 intergenic region of the animal genome, or a homologue thereof; a DNA containing a foreign DNA wherein the DNA has been inserted between the two essentially identical XB fragments or homologues thereof; a vector, animal cell, or nonhuman mammalian animal containing said DNA; and use of the vector, animal cell, or nonhuman mammalian animal for production of a substance or therapy.