The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2015
Filed:
Jul. 30, 2010
Francois Voelker, Montrond les Bains, FR;
Laurence Dumon-seignovert, Pont du Chateau, FR;
Isabelle Meynial-salles, Fourquevaux, FR;
Philippe Soucaille, Deyme, FR;
Francois Voelker, Montrond les Bains, FR;
Laurence Dumon-Seignovert, Pont du Chateau, FR;
Isabelle Meynial-Salles, Fourquevaux, FR;
Philippe Soucaille, Deyme, FR;
Metabolic Explorer, Saint Beauzire, FR;
Abstract
The present invention concerns a method for the production of 1,2-propanediol, comprising culturing a microorganism modified for an improved production of 1,2-propanediol in an appropriate culture medium and recovery of the 1,2-propanediol which may be further purified wherein the microorganism expresses a glycerol dehydrogenase (GlyDH) enzyme the inhibition of which activity by NAD+ and/or its substrate and/or its product is reduced. The present invention also relates to a mutant glycerol dehydrogenase (GlyDH) comprising at least one amino acid residue in the protein sequence of the parent enzyme replaced by a different amino acid residue at the same position wherein