The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2015
Filed:
Sep. 19, 2012
Aseptika Ltd, Huntingdon, Cambridgeshire, GB;
Kevin Andrew Auton, Huntingdon, GB;
Aseptika Ltd, Cambridgeshire, GB;
Abstract
Methods of determining levels of activity of bacteria in the lungs of patients are described, in which levels of a marker of a bacterial iron scavenging processes (for example, siderophores) and levels of a secreted bacterial protein are measured over time. Changes in the measured levels over time allow levels of bacterial activity to be determined, and exacerbations of bacterial infection to be predicted and/or monitored. Additional markers may also be used. The methods of the invention may also be used for monitoring effectiveness of antibiotic treatment of lung infection. The invention is particularly useful for monitoringlevels in lungs of cystic fibrosis patients. Kits for use in the methods are also described.