The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2015

Filed:

Dec. 15, 2006
Applicants:

Abraham J. Domb, Efrat, IL;

Joseph S. Wolnerman, Jerusalem, IL;

Inventors:

Abraham J. Domb, Efrat, IL;

Joseph S. Wolnerman, Jerusalem, IL;

Assignee:

Axiomedic Ltd., Gilbraltar, GI;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 65/00 (2009.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 31/045 (2006.01); A61K 31/56 (2006.01); A61K 33/18 (2006.01); A61K 36/18 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 9/006 (2013.01); A61K 9/2086 (2013.01); A61K 31/045 (2013.01); A61K 31/56 (2013.01); A61K 33/18 (2013.01); A61K 36/18 (2013.01); A61K 45/06 (2013.01);
Abstract

Bioadhesive sticker tablets which are applied directly to vaginal, rectal and/or oral mucosa are described herein. In one embodiment, the sticker tablets are applied directly to ulcers or lesions in the oral cavity. The compositions adhere immediately upon administration, swell over time, and remain adherent to the ulcer or lesion for at least 60 minutes. The compositions can be in the form of single layer, double layer, or multilayer sticker tablets. The compositions provide immediate pain relief to the patient and promote rapid healing of the ulcer or lesion. The sticker tablet compositions contain one or more bioadhesive polymers. In one embodiment, the polymers are crosslinked polycarboxylic acids and polyols. The compositions contain at least one herbal agent and/or irritating compound, and optionally, a non-herbal active agent. The compositions can deliver an non-irritating effective dose of the agent for at least 60 minutes. The compositions described herein are stable upon storage for six months or longer.


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