The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2015
Filed:
Oct. 24, 2012
Applicant:
Endo Pharmaceuticals Solutions Inc., Chadds Ford, PA (US);
Inventor:
Alexander Schwarz, Brookline, MA (US);
Assignee:
Braeburn Pharmaceuticals BVBA SPRL, Brussels, BE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 31/433 (2006.01); A61K 9/20 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0002 (2013.01); A61K 31/433 (2013.01); A61K 9/0024 (2013.01); A61K 9/0092 (2013.01); A61K 9/2013 (2013.01); A61K 9/2054 (2013.01); A61K 45/06 (2013.01);
Abstract
A method of treating the symptoms of spasticity comprises implanting a reservoir-based drug delivery composition into a subject to systemically deliver a therapeutically effective amount of tizanidine to the subject for a long period of time (e.g., one month or one year). The drug delivery composition may include a rate-controlling excipient (e.g., an elastomeric polymer) defining a reservoir containing at least one discrete solid dosage form (e.g., one or more pellets), which includes tizanidine free base and optionally, a sorption enhancer.