The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2015

Filed:

Aug. 11, 2006
Applicants:

Hisayuki Nomiyama, Kumamoto, JP;

Toshio Kukita, Fukuoka, JP;

Yoshiharu Hiruma, Tokyo, JP;

Inventors:

Hisayuki Nomiyama, Kumamoto, JP;

Toshio Kukita, Fukuoka, JP;

Yoshiharu Hiruma, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C12Q 1/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C07K 16/28 (2013.01); A61K 2039/505 (2013.01); C07K 2316/96 (2013.01); C12Q 1/6811 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/108 (2013.01); C07K 2317/34 (2013.01);
Abstract

The present invention relates to a method of detecting metabolic bone disorders using a gene expressed at a high level in osteoclasts, a method of screening for a compound effective for treatment and/or prevention of metabolic bone disorders, and a pharmaceutical composition for treatment and/or prevention of metabolic bone disorders. Specifically, the present invention relates to a method of detecting metabolic bone disorders using expression of the human DC-STAMP gene as an indicator, a pharmaceutical composition containing an antibody which is capable of specifically recognizing human DC-STAMP and suppressing formation of osteoclasts, and so forth.


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