The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2015
Filed:
Mar. 09, 2012
Naoya Fujita, Tokyo, JP;
Yuya Nakazawa, Tokyo, JP;
Satoshi Takagi, Tokyo, JP;
Japanese Foundation for Cancer Research, Tokyo, JP;
LSIP, LLC, Tokyo, JP;
Abstract
The present invention provides a monoclonal antibody or a functional fragment thereof, capable of recognizing Aggrus epitope that includes an amino-acid sequence represented by a sequence ID 1, 3, or 4, and the monoclonal antibody or the functional fragment thereof produced from a hybridoma with accession number of FERM BP-11446, FERM BP-11447, FERM BP-11448 or FERM BP-11449. The present invention provides the hybridoma, and further an Aggrus-CLEC-2 binding inhibitor and a pharmaceutical composition for inhibition of platelet aggregation, prevention of cancer metastasis, or treatment of tumor or cancer, including the monoclonal antibody or the functional fragment thereof.