The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2015

Filed:

Apr. 15, 2013
Applicants:

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Givat Ram, Jerusalem, IL;

Hadasit Medical Research Services and Development Ltd., Jerusalem, IL;

Ben-gurion University of the Negev Research and Development Authority, Beer Sheva, IL;

Inventors:

Ofer Mandelboim, Shoham, IL;

Angel Porgador, Lehavim, IL;

Yaakov Naparstek, Jerusalem, IL;

Chamutal Gur, Jerusalem, IL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); C07K 14/705 (2006.01); A61P 3/10 (2006.01); A61K 39/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); C07K 14/705 (2013.01); C07K 14/70503 (2013.01); C07K 16/2803 (2013.01); C07K 16/2851 (2013.01); A61K 2039/505 (2013.01); C07K 2319/30 (2013.01); A61K 38/00 (2013.01);
Abstract

The invention relates to use of the natural cytotoxicity receptor NKp46 for preventing and treating diabetes, including type I diabetes (TID) and type 2 diabetes. In particular, the invention provides compositions comprising a fragment of the extracellular region of NKp46 for preventing the onset and progression of diabetes.


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