The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2015
Filed:
Jun. 21, 2006
Applicants:
Dirk Vetter, Heidelberg, DE;
Harald Rau, Heidelberg, DE;
Thomas Wegge, Heidelberg, DE;
Ulrich Hersel, Heidelberg, DE;
Inventors:
Dirk Vetter, Heidelberg, DE;
Harald Rau, Heidelberg, DE;
Thomas Wegge, Heidelberg, DE;
Ulrich Hersel, Heidelberg, DE;
Assignee:
Ascendis Pharma GmbH, Hellerup, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/74 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48215 (2013.01);
Abstract
A polymeric prodrug is described which comprises at least one polymer attached via at least one permanent bond to a bicine linker. The bicine linker is attached via a temporary linkage to an amine containing biologically active moiety. The amine containing biologically active moiety—such as a drug—can be released by cleaving the temporary linkage.