The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2015

Filed:

Mar. 02, 2012
Applicants:

Nader Pourmand, Scotts Valley, CA (US);

Boaz Vilozny, Santa Cruz, CA (US);

Paolo Actis, Santa Cruz, CA (US);

R. Adam Seger, Santa Cruz, CA (US);

Bakthan Singaram, Santa Cruz, CA (US);

Inventors:

Nader Pourmand, Scotts Valley, CA (US);

Boaz Vilozny, Santa Cruz, CA (US);

Paolo Actis, Santa Cruz, CA (US);

R. Adam Seger, Santa Cruz, CA (US);

Bakthan Singaram, Santa Cruz, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); G01N 27/333 (2006.01); B82Y 35/00 (2011.01); B01L 3/02 (2006.01); B01L 3/00 (2006.01); G01N 33/487 (2006.01); G01Q 60/44 (2010.01);
U.S. Cl.
CPC ...
B82Y 35/00 (2013.01); B01L 3/021 (2013.01); B01L 3/50273 (2013.01); G01N 33/48721 (2013.01); G01Q 60/44 (2013.01); B01L 2300/0896 (2013.01);
Abstract

Disclosed are methods and devices for detection of ion migration and binding, utilizing a nanopipette adapted for use in an electrochemical sensing circuit. The nanopipette may be functionalized on its interior bore with metal chelators for binding and sensing metal ions or other specific binding molecules such as boronic acid for binding and sensing glucose. Such a functionalized nanopipette is comprised in an electrical sensor that detects when the nanopipette selectively and reversibly binds ions or small molecules. Also disclosed is a nanoreactor, comprising a nanopipette, for controlling precipitation in aqueous solutions by voltage-directed ion migration, wherein ions may be directed out of the interior bore by a repulsing charge in the bore.


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