The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2015

Filed:

Feb. 27, 2014
Applicant:

Comentis, Inc., South San Francisco, CA (US);

Inventors:

Ryosuke Munakata, Tokyo, JP;

Makoto Inoue, Tokyo, JP;

Hiroaki Tominaga, Tokyo, JP;

Shingo Yamasaki, Tokyo, JP;

Yasuhiro Shina, Tokyo, JP;

Kiyohiro Samizu, Tokyo, JP;

Hisao Hamaguchi, Tokyo, JP;

Lin Hong, Edmond, OK (US);

Assignee:

CoMentis, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 263/52 (2006.01); C07D 493/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for preventing or treating diseases or conditions associated with and/or mediated by β-secretase activity, hydrolysis of a β-secretase site of a β-amyloid precursor protein, and/or β-amyloid protein accumulation, including a pharmaceutical composition for preventing or treating diseases including, but not limited to, Glaucoma, MCI (Mild cognitive impairment) or Alzheimer's disease, especially, Alzheimer's disease.


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