The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2015

Filed:

Aug. 31, 2011
Applicants:

Kevin S. Currie, North Branford, CT (US);

Xiaojing Wang, Foster City, CA (US);

Wendy B. Young, San Mateo, CA (US);

Inventors:

Kevin S. Currie, North Branford, CT (US);

Xiaojing Wang, Foster City, CA (US);

Wendy B. Young, San Mateo, CA (US);

Assignees:

Genetech, Inc, South San Francisco, CA (US);

Gilead Connecticut, Inc., Foster City, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/501 (2006.01); C07D 237/02 (2006.01); C07D 403/14 (2006.01); C07D 487/04 (2006.01); C07D 495/04 (2006.01); C07D 513/04 (2006.01); A61K 31/549 (2006.01); A61K 31/553 (2006.01); A61K 45/06 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01); C07D 513/04 (2013.01); A61K 31/501 (2013.01); A61K 31/549 (2013.01); A61K 31/553 (2013.01); A61K 45/06 (2013.01); C07D 519/00 (2013.01);
Abstract

Pyridazinone compounds of Formula I including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.


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