The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2015
Filed:
Jun. 16, 2008
Hidenori Akatsuka, Osaka-fu, JP;
Hiroshi Sugama, Osaka-fu, JP;
Nobumasa Awai, Osaka-fu, JP;
Takayuki Kawaguchi, Osaka-fu, JP;
Yoichi Takahashi, Osaka-fu, JP;
Toru Iijima, Osaka-fu, JP;
Jingkang Shen, Shanghai, CN;
Guangxin Xia, Shanghai, CN;
Jianshu Xie, Shanghai, CN;
Hidenori Akatsuka, Osaka-fu, JP;
Hiroshi Sugama, Osaka-fu, JP;
Nobumasa Awai, Osaka-fu, JP;
Takayuki Kawaguchi, Osaka-fu, JP;
Yoichi Takahashi, Osaka-fu, JP;
Toru Iijima, Osaka-fu, JP;
Jingkang Shen, Shanghai, CN;
Guangxin Xia, Shanghai, CN;
Jianshu Xie, Shanghai, CN;
Shanghai Pharmaceuticals Holding Co., Ltd., Shanghai, CN;
Mitsubishi Tanabe Pharma Corporation, Osaka-Shi, JP;
Abstract
The present invention provides a morpholine derivative of the formula [I]; wherein Ris a substituted alkyl group, an optionally substituted aryl group, an optionally substituted heterocyclo group, a cycloalkyl group or an alkyl group; Ris a substituted alkyl group, an optionally substituted aryl group, an optionally substituted heterocyclo group, an optionally substituted alkylcarbonyl group, an optionally substituted arylcarbonyl group, an optionally substituted heterocyclo-substituted carbonyl group or a cycloalkylcarbonyl group; T is a methylene group or a carbonyl group; R, R, Rand Rare the same or different and a hydrogen atom, an optionally substituted carbamoyl group or an optionally substituted alkyl group;or pharmaceutically acceptable salts thereof. These compounds are useful as a renin inhibitor.