The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2015

Filed:

Dec. 09, 2010
Applicants:

Yona Geffen, Doar-Na Lachish Tzafon-Moshav Nir Banim, IL;

Kinneret Savitsky, Tel-Aviv, IL;

Abraham Nudelman, Rechovot, IL;

Ada Rephaeli, Herzlia, IL;

Irit Gil-ad, Herzlia, IL;

Abraham Weizman, Tel-Aviv, IL;

Inventors:

Yona Geffen, Doar-Na Lachish Tzafon-Moshav Nir Banim, IL;

Kinneret Savitsky, Tel-Aviv, IL;

Abraham Nudelman, Rechovot, IL;

Ada Rephaeli, Herzlia, IL;

Irit Gil-Ad, Herzlia, IL;

Abraham Weizman, Tel-Aviv, IL;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/54 (2006.01); C07D 279/26 (2006.01); A61K 31/5415 (2006.01);
U.S. Cl.
CPC ...
C07D 279/26 (2013.01); A61K 31/5415 (2013.01);
Abstract

Methods and articles of manufacture for use in improving a cognitive function, utilizing a conjugate comprising a first moiety having GABA agonist activity and a second moiety having CNS activity being covalently linked to the first moiety, are disclosed. Also disclosed are methods and articles of manufacture of preventing onset or inhibiting progression of a cognitive impairment or dysfunction utilizing the disclosed conjugate.


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