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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8975247 B1

PDFFull Text
Date of Patent:
Mar. 10, 2015

Filed:

Mar. 16, 2010

Methods and compositions of treating a flaviviridae family viral infection

Applicants:

Ingrid C. Choong, Los Altos, CA (US);

David Cory, Redwood City, CA (US);

Jeffrey S. Glenn, Palo Alto, CA (US);

Wenjin Yang, Foster City, CA (US);

Inventors:

Ingrid C. Choong, Los Altos, CA (US);

David Cory, Redwood City, CA (US);

Jeffrey S. Glenn, Palo Alto, CA (US);

Wenjin Yang, Foster City, CA (US);

Assignee:

The Board of Trustees of the Leland Stanford Junion University, Palo Alto, CA (US);

Attorney:

Thomas|Horstemeyer, LLP

Primary Examiner:

Craig Ricci

Assistant Examiner:

Jared D Barsky

Int. Cl.
CPC ...
A01N 43/52 (2006.01); A61K 31/415 (2006.01); A01N 43/40 (2006.01); A61K 31/445 (2006.01); A01N 43/04 (2006.01); A61K 31/70 (2006.01); A01N 43/00 (2006.01); A61K 31/55 (2006.01); A61K 31/4184 (2006.01); A61K 31/437 (2006.01); A61K 31/4965 (2006.01); A61K 45/06 (2006.01); C07D 235/06 (2006.01); C07D 235/08 (2006.01); C07D 235/10 (2006.01); C07D 235/14 (2006.01); C07D 235/16 (2006.01); C07D 235/28 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 405/06 (2006.01); C07D 409/06 (2006.01); C07D 413/06 (2006.01); C07D 417/04 (2006.01); C07D 471/08 (2006.01); C07D 491/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4184 (2013.01); A61K 31/437 (2013.01); A61K 31/4965 (2013.01); A61K 45/06 (2013.01); C07D 235/06 (2013.01); C07D 235/08 (2013.01); C07D 235/10 (2013.01); C07D 235/14 (2013.01); C07D 235/16 (2013.01); C07D 235/28 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01); C07D 405/06 (2013.01); C07D 409/06 (2013.01); C07D 413/06 (2013.01); C07D 417/04 (2013.01); C07D 471/08 (2013.01); C07D 491/04 (2013.01);
Abstract

Clemizole and clemizole analog compounds, and pharmaceutical compositions of the same, are useful in methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of inhibiting HCV replication in a host, methods of inhibiting the binding of NS4B polypeptide to the 3'UTR of HCV negative strand RNA in a host, and methods of treating liver fibrosis in a host.

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