The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2015

Filed:

Mar. 13, 2013
Applicant:

Oncomed Pharmaceuticals, Inc., Redwood City, CA (US);

Inventors:

Austin L. Gurney, San Francisco, CA (US);

Aaron Ken Sato, Burlingame, CA (US);

Fumiko Takada Axelrod, Palo Alto, CA (US);

Timothy Charles Hoey, Hillsborough, CA (US);

Sanjeev H. Satyal, San Carlos, CA (US);

Satyajit Sujit Kumar Mitra, South Pasadena, CA (US);

Assignee:

OncoMed Pharmaceuticals, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); A61K 38/00 (2006.01); C07K 16/30 (2006.01); A61K 31/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C07K 16/28 (2006.01); G01N 33/50 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 31/00 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); C07K 16/2863 (2013.01); G01N 33/5011 (2013.01); A61K 2039/505 (2013.01); C07K 2299/00 (2013.01); C07K 2317/21 (2013.01); C07K 2317/30 (2013.01); C07K 2317/55 (2013.01); C07K 2317/92 (2013.01); C07K 2319/30 (2013.01); C07K 2317/34 (2013.01);
Abstract

Novel anti-cancer agents, including, but not limited to, antibodies, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. Methods of using the agents or antibodies, such as methods of using the agents or antibodies to inhibit Wnt signaling and/or inhibit tumor growth are further provided.


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