The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2015

Filed:

Nov. 23, 2006
Applicants:

Andrew Cox, Ottawa, CA;

Dhamodharan Neelamegan, Ottawa, CA;

Ian Schoenhofen, Ottawa, CA;

Frank St. Michael, Ottawa, CA;

James Richards, Ottawa, CA;

Inventors:

Andrew Cox, Ottawa, CA;

Dhamodharan Neelamegan, Ottawa, CA;

Ian Schoenhofen, Ottawa, CA;

Frank St. Michael, Ottawa, CA;

James Richards, Ottawa, CA;

Assignee:

National Research Council of Canada, Winnipeg, Manitoba, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/26 (2006.01); A61K 39/385 (2006.01); C12Q 1/34 (2006.01); C12N 9/14 (2006.01); C12N 5/07 (2010.01);
U.S. Cl.
CPC ...
Abstract

Novel enzymes, processes and antigenic structures useful in producing vaccines and compounds useful in combating gram-negative bacteria are described. Enzymes were isolated from the slime moldand used to specifically degrade lipopolysaccharide (LPS). Enzymatic degradation permits residues of the LPS molecule, including immunogenic epitopes of the core oligosaccharide portion of the LPS, to remain unmodified during this enzymatic removal of fatty acids from the lipid A region of the LPS molecule.


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