The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2015
Filed:
Sep. 10, 2009
Applicants:
Manel Maria Cascallo Piqueras, Barcelona, ES;
Alena Gros, Barcelona, ES;
Ramon Alemany Bonastre, Barcelona, ES;
Inventors:
Manel Maria Cascallo Piqueras, Barcelona, ES;
Alena Gros, Barcelona, ES;
Ramon Alemany Bonastre, Barcelona, ES;
Assignee:
Institut CataláD'oncologia, , ES;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/01 (2006.01); A61K 48/00 (2006.01); C12N 15/861 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to an adenovirus wherein said adenovirus replicates and it contains a mutation in the endoplasmic reticulum retention domain of E3-19K, and to the use of said mutant in treating cancer. Said mutant virus may also contain other mutations and insertions of DNA sequences used to confer selectivity and antitumor potency. The invention has application in the field of cancer therapy.