The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2015

Filed:

Mar. 13, 2013
Applicant:

Gilead Pharmasset Llc, Foster City, CA (US);

Inventors:

Robert William Scott, San Mateo, CA (US);

Fang Wang, Foster City, CA (US);

Bing Shi, Redwood City, CA (US);

Erik Mogalian, San Francisco, CA (US);

Assignee:

Gilead Pharmasset LLC, Foster City, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); A61K 31/4184 (2006.01); A61K 31/7056 (2006.01); A61K 31/381 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4184 (2013.01); C07D 403/14 (2013.01); A61K 31/7056 (2013.01); A61K 31/381 (2013.01); C07D 471/08 (2013.01);
Abstract

Amorphous and crystalline solid forms of the anti-HCV compound (1-{3-[6-(9,9-difluoro-7-{2 -[5-(2-methoxycarbonylamino-3-methyl-butyryl)-5-aza-spiro[2.4]hept-6-yl]-3H-imidazol-4-yl}-9H-fluoren-2-yl)-1H-benzoimidazol-2-yl]-2-aza-bicyclo[2.2.1]heptane-2-carbonyl}-2-methyl -propyl)-carbamic acid methyl ester (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the amorphous and crystalline forms.


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