The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2015
Filed:
Jan. 31, 2012
Osamu Onomura, Nagasaki, JP;
Yutaro Tsuda, Nagasaki, JP;
Masami Kuriyama, Nagasaki, JP;
Toshiharu Yanagi, Hyogo, JP;
Kazuya Kodama, Hyogo, JP;
Osamu Onomura, Nagasaki, JP;
Yutaro Tsuda, Nagasaki, JP;
Masami Kuriyama, Nagasaki, JP;
Toshiharu Yanagi, Hyogo, JP;
Kazuya Kodama, Hyogo, JP;
Nagasaki University, Nagasaki, JP;
Abstract
Provided is a process for producing an optically active compound represented by Formula (3): (wherein Ris an alkyl group, an alkynyl group, an alkenyl group, an aliphatic heterocyclic group, a cycloalkyl group, an aryl group, an aralkyl group, or an aromatic heterocyclic group, and any hydrogen atom of Rmay be replaced with a substituent; Ris a hydrogen atom or a group which is not reactive in the reaction below; and * represents a chiral center) or a salt thereof by subjecting a compound represented by Formula (1): (wherein Rand Rhave the same meanings as defined in Formula (3)) to a ring closure reaction in the presence of a chiral ligand having 1 or more coordination sites, a Lewis acid represented by Formula (2):MZ  (2)(wherein M is a metal ion, Z is a counter anion of M, and m and n are integers of 1 to 4), and a sulfonyl halide having an optionally substituted alkyl or phenyl group.