The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2015

Filed:

Jun. 28, 2011
Applicants:

Michael Chorev, Chestnut Hill, MA (US);

Bertal Huseyin Aktas, Newton, MA (US);

Jose A. Halperin, Brookline, MA (US);

Gerhard Wagner, Chestnut Hill, MA (US);

Inventors:

Michael Chorev, Chestnut Hill, MA (US);

Bertal Huseyin Aktas, Newton, MA (US);

Jose A. Halperin, Brookline, MA (US);

Gerhard Wagner, Chestnut Hill, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/02 (2006.01); C07D 277/38 (2006.01); C07D 241/02 (2006.01); A61K 31/381 (2006.01); A61K 31/496 (2006.01); C07D 277/84 (2006.01); C07D 233/88 (2006.01); C07D 263/48 (2006.01); C07D 277/50 (2006.01); C07D 417/04 (2006.01); C07D 417/10 (2006.01); C07D 417/12 (2006.01); C07D 277/30 (2006.01); C07D 277/42 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 277/84 (2013.01); C07D 233/88 (2013.01); C07D 263/48 (2013.01); C07D 277/50 (2013.01); C07D 417/04 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01); C07D 277/30 (2013.01); C07D 277/42 (2013.01); C07D 513/04 (2013.01);
Abstract

Compositions and methods for inhibiting translation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, (4) disorders associated with viral infections, and/or (5) non-proliferative metabolic disorders such as type II diabetes where inhibition of translation initiation is beneficial using the compounds disclosed herein.


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