The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2015
Filed:
Aug. 10, 2007
Applicants:
Marc Blouin, St. Lazare-de-Vaudreuil, CA;
Jason Burch, Westmount, CA;
Yongxin Han, Kirkland, CA;
Christophe Mellon, L'Ile Bizard, CA;
Inventors:
Marc Blouin, St. Lazare-de-Vaudreuil, CA;
Jason Burch, Westmount, CA;
Yongxin Han, Kirkland, CA;
Christophe Mellon, L'Ile Bizard, CA;
Assignee:
Merck Frosst Canada Ltd., Kirkland, Quebec, CA;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); A61K 31/381 (2006.01); A61P 29/00 (2006.01); C07D 333/38 (2006.01); C07D 409/12 (2006.01);
U.S. Cl.
CPC ...
C07D 409/12 (2013.01); C07D 333/38 (2013.01);
Abstract
The invention is directed to thiophenecarboxamide derivatives of formulae I and II as EP4 receptor ligands, antagonists or agonists, useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis, cancer and glaucoma. Pharmaceutical compositions and methods of use are also included. (Formulas I and II).