The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2015

Filed:

Jul. 19, 2013
Applicants:

Calitor Sciences, Llc, Newbury Park, CA (US);

Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;

Inventors:

Ning Xi, Newbury Park, CA (US);

Yanjun Wu, Dongguan, CN;

Min Liao, Dongguan, CN;

Yanming Feng, Dongguan, CN;

Assignees:

Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;

Calitor Sciences, LLC, Newbury Park, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61K 31/444 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); A61K 31/4439 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 413/14 (2013.01); A61K 31/4439 (2013.01); A61K 31/444 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention provides novel substituted pyrazolone compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.


Find Patent Forward Citations

Loading…