The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2015

Filed:

Apr. 07, 2011
Applicants:

Huw Davies, Duluth, GA (US);

Dabashis Ghosh, Syracuse, NY (US);

Daniel Morton, Dereham, GB;

Inventors:

Huw Davies, Duluth, GA (US);

Dabashis Ghosh, Syracuse, NY (US);

Daniel Morton, Dereham, GB;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07J 75/00 (2006.01); A61K 31/5685 (2006.01); C07J 1/00 (2006.01); C07J 41/00 (2006.01); A61K 45/06 (2006.01); C07J 53/00 (2006.01); C07J 51/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5685 (2013.01); C07J 1/0011 (2013.01); C07J 41/0005 (2013.01); A61K 45/06 (2013.01); C07J 75/00 (2013.01); C07J 53/001 (2013.01); C07J 51/00 (2013.01);
Abstract

The disclosure relates to novel C4 and C6 substituted androst-4-ene diones as well as andros-1,4-diene diones and derivatives thereof, their process of preparation, pharmaceutical compounds containing them, and the use of said compounds for the treatment of hormone-related disorders in mammals. This includes hormone-dependent cancers, particularly those caused by elevated levels of estrogen and its intermediates. These compounds can also be used in the treatment of other hormone-related disorders, including benign prostatic hyperplasia, cardiovascular disease, and neurodegenerative disorders.


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