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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8969303 B1

PDFFull Text
Date of Patent:
Mar. 03, 2015

Filed:

Feb. 04, 2011

Tocotrienol esters

Applicants:

Khalid A. El Sayed, West Monroe, LA (US);

Paul W. Sylvester, West Monroe, LA (US);

Inventors:

Khalid A. El Sayed, West Monroe, LA (US);

Paul W. Sylvester, West Monroe, LA (US);

Assignee:

First Tech International Limited, Hong Kong, CN;

Attorneys:

John B. Edel

Edel Patents LLC

Primary Examiner:

Anna Pagonakis

Int. Cl.
CPC ...
A01N 43/16 (2006.01); A61K 31/355 (2006.01); A61K 38/00 (2006.01); A61P 35/00 (2006.01); C07D 311/72 (2006.01); A61K 31/19 (2006.01); A61K 31/192 (2006.01);
U.S. Cl.
CPC ...
C07D 311/72 (2013.01); A61K 31/19 (2013.01); A61K 31/192 (2013.01); A61K 31/355 (2013.01);
Abstract

Esters of tocotrienols having pharmacological activities pertinent to the treatment of breast cancer and other forms of cancer are disclosed herein. Among those compounds is (Z)-4-oxo-4-((R)-2,5,7,8-tetramethyl-2-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)chroman-6-yloxy)but-2-enoic acid. Tocotrienol esters were used to inhibit the growth and migration of +SA mammary epithelial cells and highly metastatic human breast cancer MDA-MB-231 cells respectively.

Find Patent Forward Citations

El Sayed, Khalid. (2015). Tocotrienol esters (U.S. Patent No. 8969303). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8969303

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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