The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2015
Filed:
Jun. 08, 2012
Felix Karim, Walnut Creek, CA (US);
Gregory Bell, Tiburon, CA (US);
Felix Karim, Walnut Creek, CA (US);
Gregory Bell, Tiburon, CA (US);
KAI Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
Methods for modulating serum phosphorus levels are described, wherein calcimimetic agents are administered to a subject in need thereof. In one embodiment, the compound is cinacalcet, and in other embodiments the compound is comprised of a contiguous sequence of subunits, X—X—X—X—X—X—X, wherein the Xsubunit comprises a thiol-containing moiety and the distribution of charge on the X-Xsubunits. The compound, when administered at selected times to a patient undergoing dialysis, lowers serum phosphorus levels, relative to pre-dosing levels, and achieves a sustained reduced level for a period of time after administration.