The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2015

Filed:

Aug. 02, 2010
Applicants:

Masaru Matsumoto, Gunma, JP;

Masako Matsumoto, Gunma, JP;

Takeshi Hanada, Saitama, JP;

Naomi Wakabayashi, Gunma, JP;

Inventors:

Masaru Matsumoto, Gunma, JP;

Masako Matsumoto, Gunma, JP;

Takeshi Hanada, Saitama, JP;

Naomi Wakabayashi, Gunma, JP;

Assignees:

Daiichi Sankyo Co., Ltd., Tokyo, JP;

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/02 (2006.01); A61K 9/00 (2006.01); A61K 38/25 (2006.01); A61K 47/10 (2006.01); A61K 47/12 (2006.01); A61K 47/22 (2006.01); A61K 47/26 (2006.01); A61K 47/40 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 38/25 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/22 (2013.01); A61K 47/26 (2013.01); A61K 47/40 (2013.01);
Abstract

An effective liquid preparation achieves high bioavailability (BA) of physiologically active peptides or proteins, including ghrelins, that are administered as drugs. Also provided is a method for improving the BA of physiologically active peptides or proteins, including ghrelins, that are subcutaneously injected in aqueous solutions. The liquid preparation contains: a physiologically active peptide or protein, such as ghrelins, as an active ingredient; an acid solution including one or a combination of two or more selected form the group consisting of acetic acid, lactic acid, phosphoric acid, glycine, citric acid, hydrochloric acid, propionic acid, butyric acid, benzoic acid and salts thereof; an alcohol; and a polar organic liquid including one or a combination of two or more selected from the group consisting of N-methyl-2-pyrrolidone, dimethylformamide, dimethylsulfoxide and methylparaben.


Find Patent Forward Citations

Matsumoto, Masaru. (2015). Liquid preparation of physiologically active peptide (U.S. Patent No. 8969298). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8969298

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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