The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2015
Filed:
Sep. 12, 2007
Yong-ji Chung, Yongin-si, KR;
Young Deug Kim, Sihung-si, KR;
Eun MI Kim, Jeollanam-do, KR;
Jun Young Choi, Gunpo-si, KR;
Jin Seuk Kim, Seoul, KR;
Sang Su Song, Seoul, KR;
Kyoung MI Cho, Cheonan-si, KR;
Yong-Ji Chung, Yongin-si, KR;
Young Deug Kim, Sihung-si, KR;
Eun Mi Kim, Jeollanam-do, KR;
Jun Young Choi, Gunpo-si, KR;
Jin Seuk Kim, Seoul, KR;
Sang Su Song, Seoul, KR;
Kyoung Mi Cho, Cheonan-si, KR;
Caregen Co., Ltd, Gunpo-si, Gyeonggi-do, KR;
Abstract
The present invention relates to a GFP-CAP peptide having an amino acid sequence derived from TGF-β1 (transforming growth factor-β1) and a cell adhesion sequence, wherein the amino acid sequence derived from TGF-β1 consists of the amino acid sequence of SEQ ID NO:1 and the TGFP-CAP peptide is represented by the following formula I: Ile-Trp-Ser-Leu-Asp-Thr-Gln-Tyr-Cell adhesion sequence (I). The TGFP-CAP peptide of the present invention exhibits excellent anti-angiogenic activity. In addition, the TGFP-CAP peptide of the present invention prevents effectively melanin generation in skin to have skin whitening effects. The present peptide shows much higher stability and permeability to skin than natural-occurring TGF-β1. Such plausible activities and safety of the present peptide enable advantageously to application to drugs, quasi-drugs and cosmetics.