The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2015

Filed:

Jul. 30, 2010
Applicants:

François Voelker, Montrond les Bains, FR;

Laurence Dumon-seignovert, Pont du Chateau, FR;

Philippe Soucaille, Deyme, FR;

Inventors:

François Voelker, Montrond les Bains, FR;

Laurence Dumon-Seignovert, Pont du Chateau, FR;

Philippe Soucaille, Deyme, FR;

Assignee:

Metabolic Explorer, Saint Beauzire, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/26 (2006.01); C12P 1/00 (2006.01); C12N 9/04 (2006.01); C12N 9/88 (2006.01); C12P 7/18 (2006.01);
U.S. Cl.
CPC ...
C12P 7/26 (2013.01); C12N 9/0006 (2013.01); C12N 9/88 (2013.01); C12P 7/18 (2013.01); C12Y 101/01002 (2013.01); C12Y 101/01006 (2013.01); C12Y 402/03003 (2013.01);
Abstract

The present invention concerns a method for the production of a biochemical selected among acetol and 1,2-propanediol, 1,3-propanediol, ethylene glycol and 1,4-butanediol comprising culturing a microorganism modified for an improved production of the biochemical selected among acetol and 1,2-propanediol, 1,3-propanediol, ethylene glycol and 1,4-butanediol in an appropriate culture medium and recovery of the desired biochemical which may be further purified wherein the microorganism expresses a YqhD enzyme which catalytic efficiency toward NADPH is increased. The present invention also relates to a mutant YqhD enzyme comprising at least one amino acid residue in the protein sequence of the parent enzyme replaced by a different amino acid residue at the same position wherein


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