The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2015
Filed:
Mar. 03, 2009
Stefan H. Bossmann, Manhattan, KS (US);
Deryl L. Troyer, Manhattan, KS (US);
Matthew T. Basel, Manhattan, KS (US);
Stefan H. Bossmann, Manhattan, KS (US);
Deryl L. Troyer, Manhattan, KS (US);
Matthew T. Basel, Manhattan, KS (US);
Kansas State University Research Foundation, Manhattan, KS (US);
Abstract
The present invention provides a diagnostic reagent or assay for assessing the activity of a protease in vivo or in vitro and methods of detecting the presence of a cancerous or precancerous cell. The assays are comprised of two particles linked via an oligopeptide linkage that comprises a consensus sequence specific for the target protease. Cleavage of the sequence by the target protease can be detected visually or using various sensors, and the diagnostic results can be correlated with cancer prognosis.