The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2015

Filed:

Nov. 12, 2010
Applicants:

Margaret A. Shipp, Wellesley, MA (US);

Jing Ouyang, Chestnut Hill, MA (US);

Kunihiko Takeyama, Tokyo, JP;

Jeffery L. Kutok, Natick, MA (US);

Scott J. Rodig, Westwood, MA (US);

Gabriel Rabinovich, Ciudad De Buenos Aires, AR;

Diego Omar Croci Russo, Provincia De Buenos Aires, AR;

Mariana Salatino, Buenos Aires, AR;

Inventors:

Margaret A. Shipp, Wellesley, MA (US);

Jing Ouyang, Chestnut Hill, MA (US);

Kunihiko Takeyama, Tokyo, JP;

Jeffery L. Kutok, Natick, MA (US);

Scott J. Rodig, Westwood, MA (US);

Gabriel Rabinovich, Ciudad De Buenos Aires, AR;

Diego Omar Croci Russo, Provincia De Buenos Aires, AR;

Mariana Salatino, Buenos Aires, AR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C12N 5/20 (2006.01); C07K 16/18 (2006.01); C07K 16/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); C07K 16/22 (2013.01); A61K 2039/505 (2013.01); C07K 2317/34 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01);
Abstract

The present invention is based, in part, on the discovery that galectin-1 (Gal1) plays a role in viral-associated PTLD, e.g., EBV-associated PTLD and hypoxia associated angiogenesis disorders. Accordingly, the invention relates to compositions, kits, and methods for diagnosing, prognosing, monitoring, treating and modulating viral-associated PTLD, e.g., EBV-associated PTLD and hypoxia associated angiogenesis disorders.


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