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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8968716 B1

PDFFull Text
Date of Patent:
Mar. 03, 2015

Filed:

Sep. 02, 2010

In situ-forming hydrogel for tissue adhesives and biomedical use thereof

Applicants:

Ki-dong Park, Seoul, KR;

Yoon-ki Joung, Incheon, KR;

Kyung-min Park, Anyang-si, KR;

Eu-gene Lih, Seoul, KR;

Inventors:

Ki-Dong Park, Seoul, KR;

Yoon-Ki Joung, Incheon, KR;

Kyung-Min Park, Anyang-si, KR;

Eu-Gene Lih, Seoul, KR;

Assignee:

Ajou University Industry-Academic Cooperation Foundation, Gyeonggi-Do, KR;

Attorney:

Revolution IP, PLLC

Primary Examiner:

Suzanne Ziska

Assistant Examiner:

Thurman Wheeler

Int. Cl.
CPC ...
A61L 24/04 (2006.01); A61L 24/08 (2006.01); A61K 38/39 (2006.01); A61K 31/722 (2006.01); A61K 31/765 (2006.01); A61K 38/02 (2006.01); A61K 38/18 (2006.01); A61K 38/27 (2006.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); A61K 38/23 (2006.01); A61K 38/25 (2006.01); A61K 38/28 (2006.01); A61K 38/31 (2006.01); A61K 38/26 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); A61K 33/24 (2006.01); A61L 24/00 (2006.01); A61L 27/18 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01);
U.S. Cl.
CPC ...
A61L 24/0042 (2013.01); A61L 24/0015 (2013.01); A61L 24/0031 (2013.01); A61L 24/046 (2013.01); A61L 27/18 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); A61L 2300/252 (2013.01); A61L 2300/256 (2013.01); A61L 2300/406 (2013.01); A61L 2300/41 (2013.01); A61L 2300/414 (2013.01); A61L 2300/416 (2013.01); A61L 2300/426 (2013.01); A61L 2300/43 (2013.01); A61L 2300/602 (2013.01);
Abstract

Disclosed herein are an in situ-forming, bioadhesive hydrogel and the medical uses thereof. Being formed by in situ crosslinking through an enzymatic reaction, the hydrogel has an advantage over conventional bioadhesive hydrogels in terms of biocompatibility. In addition, the in situ-forming bioadhesive hydrogel has excellent biocompatibility and mechanical strength and has excellent tissue adhesiveness thanks to modification with/without dopa derivatives. The hydrogel finds a variety of applications in the biomedical field, including bioadhesives or hemostats, implant substances for tissue regeneration and augmentation, carriers for delivering biologically active materials or drugs, etc.

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