The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2015

Filed:

Sep. 16, 2011
Applicants:

Patrick Roussel, Mulhouse, FR;

Jutta Heim, Ramlinsburg, CH;

Peter Schneider, Bottmingen/BL, CH;

Christian Bartels, Allschwil/BL, CH;

Yaoquan Liu, Castro Valley, CA (US);

Glen Dale, Basel, CH;

Daniel Milligan, San Francisco, CA (US);

Inventors:

Patrick Roussel, Mulhouse, FR;

Jutta Heim, Ramlinsburg, CH;

Peter Schneider, Bottmingen/BL, CH;

Christian Bartels, Allschwil/BL, CH;

Yaoquan Liu, Castro Valley, CA (US);

Glen Dale, Basel, CH;

Daniel Milligan, San Francisco, CA (US);

Assignee:

Evolva SA, Reinach, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 455/02 (2006.01); A61K 31/4375 (2006.01);
U.S. Cl.
CPC ...
C07D 455/02 (2013.01);
Abstract

Described are a series of 2-pyridone compounds as a potent and selective new class of type II topoisomerase inhibitors with broad-spectrum antimicrobial activity having the general formula (I); where R1, R2, X, and Y are defined herein Such compounds can be used in methods for treating an infection caused by a gram-positive pathogen, a gram-negative pathogen, or a drug-resistant strains thereof.


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