The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2015
Filed:
Jul. 08, 2011
Tomas Hudlicky, St. Catharines, CA;
Robert James Carroll, Herts, GB;
Hannes Leisch, Unterach am Attersee, AT;
Ales Machara, Brevnov, CZ;
Lukas Werner, Kadan, CZ;
Mary Ann Endoma-arias, Quezon, PH;
Tomas Hudlicky, St. Catharines, CA;
Robert James Carroll, Herts, GB;
Hannes Leisch, Unterach am Attersee, AT;
Ales Machara, Brevnov, CZ;
Lukas Werner, Kadan, CZ;
Mary Ann Endoma-Arias, Quezon, PH;
Brock University, St. Catharines, Ontario, CA;
Abstract
The present invention provides a method for the N-demethylation and N-functionalization of an N-methylated heterocycle such as a morphine alkaloid or tropane alkaloid. The method comprises reacting the heterocycle with an functionalization agent in the presence of a transition metal catalyst in air or in the presence of an oxidant.