The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2015

Filed:

Apr. 12, 2013
Applicant:

Gilead Connecticut, Inc., Foster City, CA (US);

Inventors:

Scott A. Mitchell, East Haven, CT (US);

Kevin S. Currie, North Branford, CT (US);

Peter A. Blomgren, North Branford, CT (US);

Jeffrey E. Kropf, Branford, CT (US);

Seung H. Lee, Branford, CT (US);

Jianjun Xu, Madison, CT (US);

Douglas G. Stafford, Niskayuna, NY (US);

Assignee:

Gilead Connecticut, Inc., Foster City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 241/36 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 519/00 (2013.01); G01N 2333/9121 (2013.01);
Abstract

Certain imidazopyrazines of Formula (I): or pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.


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