The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2015
Filed:
Oct. 30, 2006
David Charles Festus Moffat, Abingdon, GB;
Sanjay Ratilal Patel, Abingdon, GB;
Francesca Ann Day, Abingdon, GB;
Andrew James Belfield, Abingdon, GB;
Alistair David Graham Donald, Abingdon, GB;
Alan Hornsby Davidson, Abingdon, GB;
Alan Hastings Drummond, Abingdon, GB;
David Charles Festus Moffat, Abingdon, GB;
Sanjay Ratilal Patel, Abingdon, GB;
Francesca Ann Day, Abingdon, GB;
Andrew James Belfield, Abingdon, GB;
Alistair David Graham Donald, Abingdon, GB;
Alan Hornsby Davidson, Abingdon, GB;
Alan Hastings Drummond, Abingdon, GB;
GlaxoSmithKline Intellectual Property Development Limited, Brentford, Middlesex, GB;
Abstract
Compounds of formula (I), and salts, N-oxides, hydrates and solvates thereof are histone deacetylase inhibitors and are useful in the treatment of cell proliferative diseases, including cancers: wherein Q, V and W independently represent —N═ or —C═; B is a divalent radical selected from (B1), (B2), (B3), (B4), (B5) and (B6). wherein the bond marked * is linked to the ring containing Q, V and W through -[Linker1]- and the bond marked ** is linked to A through -[Linker2]-; A is an optionally substituted mono-, bi- or tri-cyclic carbocyclic or heterocyclic ring system; -[Linker1]- and -[Linker2]- independently represent a bond, or a divalent linker radical; and R is (a) a radical of formula RRCHNH—Y-L-X—(CH)— or (b) a radical of formula R-L-Y—(CH)—.