The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2015

Filed:

Dec. 16, 2011
Applicants:

Sarah Ellen Ades, Boalsburg, PA (US);

Kenneth Charles Keiler, Boalsburg, PA (US);

Inventors:

Sarah Ellen Ades, Boalsburg, PA (US);

Kenneth Charles Keiler, Boalsburg, PA (US);

Assignee:

The Penn State Research Foundation, University Park, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); C12Q 1/18 (2006.01); C12Q 1/68 (2006.01); A61P 31/04 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/18 (2013.01); A61K 38/12 (2013.01); C12Q 1/6897 (2013.01); G01N 2333/195 (2013.01);
Abstract

A system, a composition, a method and a kit for identifying anti-bacterial agents are provided. The invention described herein is useful in identifying inhibitors of any bacterial stress response. Moreover, the invention can be applied to any sRNA and its target, any transcription factor and its target, and any transcription factor/sRNA pair (i.e., a transcription factor that regulates a sRNA). In particular, the present invention provides a system, a composition, a method and a kit for the identification of cyclic peptides that block the σpathway in


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