The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2015

Filed:

Mar. 01, 2012
Applicants:

Vihang A. Narkar, Houston, TX (US);

Michael Downes, San Diego, CA (US);

Ruth T. Yu, La Jolla, CA (US);

Ronald M. Evans, La Jolla, CA (US);

Inventors:

Vihang A. Narkar, Houston, TX (US);

Michael Downes, San Diego, CA (US);

Ruth T. Yu, La Jolla, CA (US);

Ronald M. Evans, La Jolla, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/16 (2006.01); A61P 21/00 (2006.01); A61P 25/00 (2006.01); A61P 9/00 (2006.01); A61K 31/166 (2006.01); A61K 38/17 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/166 (2013.01); A61K 38/177 (2013.01); A61K 48/00 (2013.01);
Abstract

This application provides methods of increasing vascularization, muscle performance, muscle rehabilitation, and/or mitochondrial activity in subjects in need thereof, by administering a therapeutically effective amount of one or more agents that increases ERRγ activity to the subject. Such agents can include one or more ERRγ agonists. In some examples the method does not require that the subject exercise, and as such, the subject may be sedentary (such as bedridden or in a wheelchair).


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