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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8962329 B1

PDFFull Text
Date of Patent:
Feb. 24, 2015

Filed:

Sep. 24, 2009

Gene cluster

Applicants:

Wen Liu, Shanghai, CN;

Nan Jiang, Shanghai, CN;

Xudong Qu, Shanghai, CN;

Inventors:

Wen Liu, Shanghai, CN;

Nan Jiang, Shanghai, CN;

Xudong Qu, Shanghai, CN;

Assignee:

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, CN;

Attorneys:

Robert C. Netter, Jr.

Kathleen D. Rigaut

Dann, Dorfman, Herrell & Skillman

Primary Examiner:

Yong Pak

Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 1/20 (2006.01); C12N 9/00 (2006.01); C07H 21/04 (2006.01); C12P 17/00 (2006.01); A61K 31/35 (2006.01); A61K 31/5025 (2006.01); C07D 491/10 (2006.01); C07K 14/36 (2006.01); C12N 15/52 (2006.01); C12P 17/18 (2006.01);
U.S. Cl.
CPC ...
C12P 17/00 (2013.01); A61K 31/35 (2013.01); A61K 31/5025 (2013.01); C07D 491/10 (2013.01); C07K 14/36 (2013.01); C12N 15/52 (2013.01); C12P 17/188 (2013.01);
Abstract

Novel isolated DNA sequences which comprise all or part of a gene cluster encoding sanglifehrin synthase, processing and regulatory genes involved in the biosynthesis of a mixed non-ribosomal peptide/polyketide compound, or mutants having altered biosynthetic capability, polypeptides or mutants thereof encoded by DNA or the mutants, vectors containing the DNA or the mutants thereof, host cells transformed with the DNA, the mutants thereof, or the vector, and a method for producing sanglifehrin compounds. Compounds with cyclophilin inhibition activity used as immunosuppressants, antivirals or cardiac protection agents.

Find Patent Forward Citations

Liu, Wen. (2015). Gene cluster (U.S. Patent No. 8962329). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8962329

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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